MULTIPLE TIME POINTS OF TRANSCRIPTOME ANALYSIS REVEALED ALTERED GENES INVOLVED IN MAINTAINING HIBERNATION IN THE HYPOTHALAMUS OF TAMIAS SIBIRICUS

Multiple time points of transcriptome analysis revealed altered genes involved in maintaining hibernation in the hypothalamus of Tamias sibiricus

Hibernation, an adaptive mechanism to extreme environmental conditions, is prevalent among mammals.Its main characteristics include reduced body temperature and metabolic rate.However, the mechanisms by which hibernating animals re-enter deep sleep during the euthermic phase to sustain hibernation remain poorly understood.We selected the Tamias sib

read more

Concentric ring optical traps for orbital rotation of particles

Optical vortices (OVs), as eigenmodes of optical orbital angular momentum, have been widely used in particle micro-manipulation.Recently, perfect optical vortices (POVs), a subclass of OVs, are gaining increasing interest life extension blueberry extract and becoming an indispensable tool in optical trapping due to their unique property of topologi

read more



CONSORT-DEFINE explanation and elaboration: recommendations for enhancing reporting quality and impact of early phase dose-finding clinical trialsResearch in context

Summary: Early phase dose-finding (EPDF) trials are key in the development of novel therapies, with their findings directly informing subsequent clinical development phases and providing valuable insights for reverse translation.Comprehensive and transparent reporting of these studies is critical for their accurate and critical interpretation, whic

read more